1. A PROGRESS-Driven Approach to Cognitive Outcomes after Traumatic Brain Injury: Advancing Equity, Diversity, and Inclusion through Knowledge Synthesis and Mobilization
- Funder: Canadian Institutes of Health Research (CIHR) – Knowledge Synthesis and Mobilization Grants – Brain Health and Reduction of Risk for Age-related Cognitive Impairment – Sex and Gender Differences.
- Contributors: Mollayeva, T, McDonald, M, Clayton, D, Colantonio, A, Einstein, G, Escobar, M, FullerThomson, E, Gately, D, Hanafy, S, Lawlor, B, McGettrick, G, Popovic, M; Study Coordinator: Tylinski Sant’Ana, T
- Summary: Traumatic brain injury (TBI) is a common injury that affects people of all walks of life. However, it affects each person differently based on unique biological and social characteristics. Our research applies a framework called PROGRESS-Plus to explore how characteristics like race, income, and residence, and others affect brain health after injury.
Patient, Caregiver, Clinician, and Community Leader Participation in Priority Setting for Brain Health Following Traumatic Brain Injury: A PROGRESS-Driven Approach to Advancing Equity, Diversity, and Inclusion
- Trainee: Rachel Spouge
Sex Differences in Mortality Following Traumatic Brain Injury: A Meta Research Study
- Trainee: Daniel Phan, Darren Tang
PROGRESS-Plus Considerations and Their Importance for Mental Health Outcomes Following Traumatic Brain Injury.
- Trainees: Yupeng Yao, Dian Zhang
Applying Machine Learning to Predict Cognitive Outcomes after Traumatic Brain Injury using PROGRESS-Plus
- Trainee: Jingwen Xu, Urooba Shaikh
2. Sex and Gender Equity in Traumatic Brain Injury: Implications for Dementia
- Funders: Global Brain Health Institute (GBHI). UK Pilot Award for Global Brain Health Leaders.
- Contributors:
- Summary: Building on prior Alzheimer’s Association-funded work, this study investigates whether biological sex or socially constructed gender drives differences in dementia risk and progression following traumatic brain injury. Using matched cohorts and a novel Gender Score, we will build predictive models to inform future prevention strategies.
Assessment of Measures used to Study Sex and Gender in Clinical and Functional Outcomes
- Trainees: Anisa Brar, Anjali Issar, Alicia Ruetas, Teodora Prnjat, Nada Ahmad, Urooba Shaikh
3. Systematic Review on Cognitive Outcomes Following Traumatic Brain Injury
- Funder: Toronto District School Board (TDSB); BRIDGE Lab
- Contributors: Fernando, M, Namungo, R, Lewczuk, M, Mollayeva, T
- Summary: Traumatic brain injury (TBI) is common occurrence affecting all types of people. Each affected person is unique, with differing backgrounds, economic class, education, race, and more, and these factors each contribute to cognitive recovery after a TBI. Using a framework, PROGRESS-Plus, which is designed to consider all of these factors and more, we examined representation and inclusivity across more than 7,000 studies.
Cognitive Outcomes after TBI Art Reflection
- Contributors: Namungo, R, Fernando, M, Lewczuk, M, Mollayeva, T
- Summary: Traumatic brain injury (TBI) is caused by an external force resulting in disruptions to normal brain function. Significant variability has been seen in recovery patterns among individuals, but it is unclear if variability is driven by social factors. Using the PROGRESS-Plus framework, we examined how well researchers reported on social characteristics of research participants across 7,000 studies.
Equity in Systematic Review of Longitudinal Studies Poster
